Live Cell Molecular Imaging Research Team
Team Leader
Akihiko Nakano
- Brief resume
- 1980
- D.Sci., University of Tokyo
- 1980
- Research Associate, National Institute of Health
- 1984
- Postdoctoral Research Associate, University of California, Berkeley, USA
- 1988
- Lecturer, University of Tokyo
- 1991
- Associate Professor, University of Tokyo
- 1997
- Chief Scientist, Molecular Membrane Biology Laboratory, RIKEN (-current)
- 2003
- Professor, Department of Biological Sciences, Graduate School of Science, University of Tokyo (-current)
- 2005
- Team Leader, Real-time Bio-imaging Research Team, RIKEN
- 2010
- Team Leader, Live Cell Molecular Imaging Research Team, RIKEN (-current)
- 2010
- Team Leader, Kibo In-cabin Research Team, RIKEN (-current)
Outline
Imaging is one of the most important methodologies of modern life science. Development of useful fluorescent/luminescence probes and the advancement of light microscope technologies enable real-time observation of living cells and tissues. We will exploit cutting-edge microscopic technologies with visible light, and observe, measure and manipulate proteins and membranes within living cells to understand mechanisms of live phenomena. We will also aim at introducing the new light sources that are created by other teams of our department into the imaging technologies of live materials.
Recent Research Topic
- Fig. 1: High 3D spatial resolution achieved by live imaging (yeast Golgi apparatus)
- Fig. 1
- Reproduced, with permission, from A. Nakano, A. Luini. Passage through the Golgi. Curr. Opin. Cell Biol. 2010, 22, 471. © (2012) Elsevier
Selected Publications
- K. Ebine, et al. A membrane trafficking pathway regulated by the plant-specific RAB GTPase ARA6, Nature Cell Biol. 2011, 13, 853.
- T. Hamamura, et al. Live cell imaging reveals the dynamics of two sperm cells during double fertilization in Arabidopsis thaliana, Curr. Biol. 2011, 21, 497.
- M. Iwai, et al. Isolation of the elusive supercomplex that drives cyclic electron flow in photosynthesis, Nature 2010, 464, 1210.
- Y. Maeda, et al. Broadly tunable UV-blue picosecond pulsed laser and its application for biological imaging, Opt. Rev. 2010, 17, 305.
- H. Iino, et al. Live imaging system for visualizing nuclear pore complex (NPC) formation during interphase in mammalian cells, Genes Cells 2010, 15, 647.
- M. Fujimoto, et al. Arabidopsis dynamin-related proteins DRP2B and DRP1A participate together in clathrin-coated vesicle formation during endocytosis, Proc. Natl. Acad. Sci. U. S. A. 2010, 107, 6094.
- I. I. Rzeznicka, et al. Duramycin-induced destabilization of a phosphatidylethanolamine monolayer at the air-water interface observed by vibrational sum-frequency generation spectroscopy, Langmuir 2010, 26, 16055.
- K. V. Tabata, et al. Visualization of cargo concentration by COPII minimal machinery in a planar lipid membrane, EMBO J. 2009, 28, 3279.
- A. Kadota, et al. Short actin-based mechanism for light-directed chloroplast movement in Arabidopsis, Proc. Natl. Acad. Sci. U. S. A. 2009, 106, 13106.
- K. Matsuura-Tokita, M. Takeuchi, A. Ichihara, K. Mikuriya, A. Nakano, Live imaging of yeast Golgi cisternal maturation, Nature 2006, 441, 1007.
Core Members
| Postdoctoral Fellow |
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| Masakazu Iwai |
Special Postdoctoral Researcher |
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| Michiyo Okamoto |
Postdoctoral Researcher |
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| Student Trainee |
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| Technical Assistant |
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| Administrative Assistant |
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| Visiting Research Staff |
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( ) indicates primary affiliation in RIKEN.
