Systems Glycobiology Research Group

Group Director

Naoyuki Taniguchi

  • D.Med.
  • Naoyuki Taniguchi
  • Brief resume
    1972
    D.Med., Hokkaido University
    1976
    Visiting Associate Professor, Cornell University, USA
    1978
    Associate Professor, Hokkaido University
    1986
    Professor/Chair, Osaka University
    2006
    Professor Emeritus/Endowed Chair Professor, Research Institute for Microbial Diseases, Osaka University
    2007
    Group Director, Systems Glycobiology Research Group, RIKEN (-current)
    2009
    Endowed Chair Professor, Institute of Scientific and Industrial Research, Osaka University
    2011
    Guest Professor, Institute of Scientific and Industrial Research, Osaka University (-current)
    2011
    Team Leader, Disease Glycoprobe Team, RIKEN (-current)

Outline

Over 50% of proteins are glycosylated, and glycosylation reaction is one of the most important post-translational modifications of proteins. The sugar chains have different kinds of functions, which we are unable to understand from research on DNA, RNA and proteins. This project focuses on the structure and functions of glycoproteins, and we aim to elucidate (1) abnormality of signaling via membrane receptor glycans, and underlying disease mechanism; (2) novel metabolic pathways of free glycans and then roles in the quality control of glycoproteins; (3) tertiary structures of glycans and their roles in molecular recognition; and (4) to develop single-molecule imaging of glycans. Through these efforts we will pursue basic research, which may develop biomarkers and therapeutics for diseases such as cancer, infectious diseases, lifestyle-related diseases and neuromuscular degenerative diseases.

Core Members

Principal Investigator add delete
Naoyuki Taniguchi Group Director    
Staff Scientist add delete
Postdoctoral Fellow add delete
Student Trainee add delete
Technical Assistant add delete
Administrative Assistant add delete
Visiting Research Staff add delete
Other Staff add delete

Please see Research Team page for other members.

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